The Psychedelic Diaries, Vol X: Mastering the macrodose
“The more one meditates upon good thoughts, the better will be one’s world and the world at large”
The Psychedelic Diaries Refresher
This series chronicles monthly macrodosing — full-dose, intentional psychedelic therapy sessions — over a five year period. Challenges, preparation, and overall impact are detailed in the volumes below.
Volume I: When you journey inward
Volume II: Five tips to prepare for a macrodose
Volume III: Entering the “Mozart Zone”
Volume IV: Seven “Mozart Zone” observations
Volume V: Making your macrodose playlist
Volume VI: Seven types of profound macrodose trips
Volume VII: Seven challenges to macrodosing
Volume VIII: Seven realizations from macrodosing
Volume IX: Seven strange aspects of macrodosing
Volume X: Mastering the macrodose
Mastering the macrodose
This all started because of a crush on a girl.
Psychedelics are our best tool for mental health, creativity, and finding purpose.
And yet, the adventure into your mind can be intimidating.
The first nine articles in these Psychedelic Diaries detailed many nuances of macrodosing... this edition will address my approach to dosage and timing.
There are 3 stages of mastering the psilocybin macrodose:
I’ll share my Sasha-Shulgin-inspired approach to each stage, followed by brief thoughts on microdosing and mushroom cultivation.
Stage 1: Getting acquainted
Get comfortable with the substance and ramp up to full dosage
Proper preparation followed by 3 trips of increasing dosage:
A 0.42g microdose with a walk in the park
2 weeks later, a half dose (1.75g – 2g) alone or with a copilot, indoors
1 month later a full dose 3.5g alone or with a copilot, indoors
Illuminations that change the trajectory of life in beautiful ways
Mind and body are now familiar with the medicine
Stage 2: Deep cleanings
Neural pathways have “gummed up” over the years. A few deep sessions will reset brain connectivity.
Alternating full and half doses, 1x a month, for 4 months
Month 1 — 3.5g alone or with a copilot, indoors
Month 2 — 1.75g alone or with a copilot, in nature
Month 3 — 3.5g alone, indoors
Month 4 — 1.75g alone, in nature
The mind will be reset with tremendous connectivity and a quieter default mode network.
The effects of the Mozart Zone will be pronounced.
Stage 3: Mind maintenance
Establish a cadence that gives the mind consistent access to full capacity.
A full or half dose on the last Saturday of each month.
Schedule 1 full dose for every 2 half doses. In other words, month 1 is a 3g–4g dose, then month 2 and 3 are half that amount. For example:
Reset the full-half-half cadence each quarter with one caveat: the mind and body may need 6-8 weeks after especially profound trips.
Alternate between these four settings:
In nature, with a copilot
Indoors, with a copilot
In nature, alone
The mind’s EQ and IQ are asymptote-close to full capacity
Drastically improved mental health
Profound impact on problem solving and creativity
Raised consciousness with a deep sense of purpose
It's fair to ask whether this is too much psychedelic therapy.
The clear answer was no for me, and research may support the 1 month cadence.
I experimented with 2, 3, and 4-month breaks... and experienced diminished results.
However, some trips are so powerful that a longer break is ideal, and needs may change over time.
After five years, I've noticed a shift. Perhaps a reduced frequency will feel appropriate.
Microdosing and growing
I utilize 2-5 smaller microdose sessions during the month:
0.07g–0.15g for complex problem solving and creativity at work
0.42g for weekend microdoses
It’s just as tough to put an upper bound on the future possibilities.
This psychedelic renaissance is a beautiful thing.
If you're ready, there’s an adventure waiting.